@Werner-19 I think the answers above already cover this but my tactic is to start each route at a starting point at some distance from my hotel (in your case this would be the first waypoint of the first road you really want to take; This allows the GPS to calculate the most efficient route from where your car/motorcycle is to that first point, highway or no highway.
My last point is then really in front of the next hotel because that is where i must end up